Research

Center for Clinical and Translational Science Announces Pilot Funding Recipients

 
LEXINGTON, Ky (Oct. 2, 2013) - The University of Kentucky Center for Clinical and Translational Science (CCTS) Pilot Funding Program announces recipients of its most recent round of pilot funding in the Collaborative Category. The mission of the Pilot Funding Program is to offer opportunities and resources necessary to support innovative intervention and early stage and collaborative research approaches in clinical and translational studies, and to promote the development of new methodologies and tools relevant to the health challenges and disparities faced by the citizens of Kentucky, Appalachia, and other rural populations.
 
Since its inception in 2007, the CCTS Pilot Funding Program has provided 45 grants totaling $1.6 million. Eleven projects supported by CCTS pilot grants have subsequently earned further funding from the National Institutes of Health, bringing an additional $6.9 million of research funding to UK. 
 
The CCTS Pilot Funding Program, which is a non-disease specific program, is itself supported by a Clinical and Translational Science Award from the National Institutes of Health.
 
CCTS-Markey Cancer Center Collaborative Award
(18 Letters of Intent submitted; 7 applicants invited to submit full applications)
 
Principal Investigator: Ren Xu, PhD
College: Pharmacy
Department/Division: Pharmacology
Title: Identify RORα as a druggable EMT suppressor
 
Principal Investigator: Thomas Dziubla, PhD
College: Engineering
Department/Division: Chemicals and Materials Engineering
Title: Pulmonary Targeting of Poly(curcumin PBAE) nanoparticles for the Prevention of Radiation Induced Pulmonary Fibrosis
 
CCTS-Barnstable Brown Diabetes and Obesity Research Center
(17 Letters of Intent submitted; 7 applicants invited to submit full applications)
 
Principal Investigator: Gregory Graf, PhD
College: Pharmacy
Department/Division: Pharmaceutical Sciences
Title: Ezetimibe & Urso combination therapy in the treatment of nonalcoholic fatty liver disease
 
Principal Investigator: Changcheng Zhou, PhD
College: Medicine
Department/Division: Graduate Center for Nutritional Sciences
Title: IKKbeta links vascular inflammation to obesity and insulin resistance
 
CCTS-Spinal Cord and Brain Injury Research Center
(9 Letters of Intent submitted; 6 applicants invited to submit full applications)
 
Principal Investigator: Lumy Sawaki, PhD
College: Medicine
Department/Division: Physical Medicine and Rehabilitation
Title: Effects of transvertebral direct current stimulation in humans
 
Principal Investigator: Edward Hall, PhD
College: Medicine
Department/Division: SCoBIRC
Title: Oxidative Damage and Calcium-Activated Proteolytic Biomarkers after Tramatic Brain Injury and Effects of Acute Cyclosporine
 
 
UK CCTS-University of Cincinnati CCTS
(8 Letters of Intent submitted; 4 applicants invited to submit full applications)
 
Principal Investigator: Sidney Whiteheart, PhD (UK)
College: Medicine
Department/Division: Molecular and Cellular Biochemistry
Principal Investigator: Alexandra Filipovich, MD (UC)
College: Medicine
Department/Division: Pediatrics
Title: Analysis of Platelet Function in Hemophagocytic Lymphohistiocytosis
 
CCTS-University of West Virginia
(7 Letters of Intent submitted; 3 applicants invited to submit full applications)
 
Principal Investigator: Scott Roth, MD (UK)
College: Medicine
Department/Division: Surgery
Principal Investigator: Bryan Richmond, MD (UC)
College: Medicine
Department/Division: Surgery
Title: Randomized Controlled Trial of Nonoperative Treatment Versus Laparoscopic Cholecystectomy for Gall bladder Dyskinesia
 
CCTS-Marshall University
(9 Letters of Intent submitted; 3 applicants invited to submit full applications)
 
Principal Investigator: Maria Serrat, PhD
College: Medicine
Department/Division: Anatomy and Pathology
Title: Temperature enhanced bone elongation in growth plates
 
CCTS Drug Discovery and Development
(21 Letters of Intent submitted; 6 applicants invited to submit full applications)
 
Principal Investigator: Vivek Ragnekar, PhD
College: Medicine
Department/Division: Radiation Medicine
Title: Development of Vimentin Inhibitors for Secretion of Par-4 and Suppression of Tumor Metastasis
 
Principal Investigator: Dave Feola, PhD
College: Pharmacy
Department/Division: Pharmacy Practice & Science
Title: Novel immune-modulatory macrolides — discovery and function
 
 
CCTS Community Engagement
(7 Letters of Intent submitted; 7 applicants invited to submit full applications)
 
Principal Investigator: Christina Studts, PhD
College: Medicine
Department/Division: Behavioral Science
Title: Preventing Conduct Disorder: Valuing Parent & Provider Perspectives in Appalachia
 
 
 
MEDIA CONTACT: Mallory Powell, mallory.powell@uky.edu