Dave Melanson

By

College: Pharmacy

Pharmacy Faculty Member's Start-Up Gets NIH Grant

Published: May 21, 2013

LEXINGTON, Ky. (May 21, 2013) — AntiOp, Inc., a start-up company launched by University of Kentucky College of Pharmacy faculty member Dan Wermeling, received a three-year, $3 million grant from the National Institutes of Health to support the development of a needle-less delivery system for opioid overdose treatment.

 

The grant, which is funded by the National Institute on Drug Abuse, will support Wermeling’s promising work in developing a naloxone nasal spray. In its injectable form, naloxone is used to reverse the effects of opioid overdose, which often occurs in those abusing heroin or prescription pain medication.

 

“I am very thankful to receive this federal funding,” said Wermeling, a faculty member in the Department of Pharmacy Practice and Science and an alumnus of the college. “The nasal delivery system for naloxone has shown great progress, and this funding will help support AntiOp’s efforts to create a delivery system that is easier to utilize for health care providers, friends and family members of those battling opioid addiction.”

 

As part of the grant, UK will coordinate the clinical trial for this naloxone formulation/delivery system. Faculty from the UK College of Pharmacy will analyze the naloxone nasal spray biopharmaceutics. Faculty from the UK College of Medicine’s Otolaryngology Department will study the impact on the nasal cavity.

 

“The peer-review vetting and awarding of federal support of this project provides further validation of the outstanding translational research being conducted by Dr. Wermeling and his collaborators at the University of Kentucky and by his company, AntiOp,” said Linda Dwoskin, associate dean for research for the UK College of Pharmacy. “Dr. Wermeling’s passion to bring naloxone nasal spray to patients who need it is inspiring, and we certainly applaud him for receiving this critical federal funding to support this endeavor.”

 

AntiOp is a “virtual” small pharmaceutical company with the sole purpose of developing the naloxone nasal spray with the goal of reducing national mortality from opioid overdoses, whether from licit or illicit usage. Wermeling supervises a team of scientific and regulatory experts at UK and from around the country to develop the product, manages the regulatory strategy, and is preparing for commercial manufacturing. AntiOp has an option to license the UK intellectual property on this product, and is currently seeking a partner to license and commercially market the product. 

 

In addition to this funding, AntiOp has received grant support from the Kentucky SBIR/STTR Matching Funds Program. The program is funded by the Kentucky Cabinet for Economic Development and Office of Commercialization and Innovation to support and incubate high-tech entrepreneurship in the Commonwealth of Kentucky.  

150370219.jpg
August
 
 
 
 
 
 
1
 
Sat
2
 
Sun
3
 
Mon
4
 
Tue
5
 
Wed
6
 
Thu
7
Curator Tour
Fri
8
 
Sat
9
 
Sun
10
 
Mon
11
 
Tue
12
 
Wed
13
 
Thu
14
 
Fri
15
 
Sat
16
 
Sun
17
 
Mon
18
We Are UK
Tue
19
 
Wed
20
 
Thu
21
Parent and Families Reception
Fri
22
K Team Meeting: K Week Overview
Big Blue U
Campus Ruckus
Getting Around Campus and Beyond
Sat
23
The Late Night Film Series Presents - Fast and Furious 7
K Team Meeting: Lunch and Campus Tour
UK Lex-Mart
Pedalpalooza
Bowman's Bash
Sun
24
Bowman's Bash
K Team Meeting: Dinner with Your K Team
Kentucky at Kroger
Mon
25
K Team Meeting: Common Reading Experience Discussion
Bicycle-Friendly Lexington
Tue
26
First Day of Classes
Don't Steal Bikes, Bro
Understanding Lexington's Bicycle Facilities
First Day of Classes
Wildcat Wellness Meditation
Wed
27
The Late Night Film Series Presents - The Wind Rises
The Late Night Film Series Presents - Avengers: Age of Ultron
Adjusting to College
Wildcat Wellness - Yoga for Relaxation
Painting and Mocktails
Terrace Time Out at the Hilary J. Boone Center
Thu
28
The Late Night Film Series Presents - Divergent
The Late Night Film Series Presents - Ex Machina
Wildcat Block Watch
Chapel Talk: Faith and Science in an Evolving World
Royalty Showcase
Fri
29
 
Sat
30
 
Sun
31
Wildcat Wellness Expressions - Inspiration Object
UK Mock Trial Informational Meeting
Mon
 
 
 
 
 

Fri, 08/28/2015

Mon, 08/31/2015

Reset Page