Dave Melanson

By

College: Pharmacy

Pharmacy Faculty Member's Start-Up Gets NIH Grant

Published: May 21, 2013

LEXINGTON, Ky. (May 21, 2013) — AntiOp, Inc., a start-up company launched by University of Kentucky College of Pharmacy faculty member Dan Wermeling, received a three-year, $3 million grant from the National Institutes of Health to support the development of a needle-less delivery system for opioid overdose treatment.

 

The grant, which is funded by the National Institute on Drug Abuse, will support Wermeling’s promising work in developing a naloxone nasal spray. In its injectable form, naloxone is used to reverse the effects of opioid overdose, which often occurs in those abusing heroin or prescription pain medication.

 

“I am very thankful to receive this federal funding,” said Wermeling, a faculty member in the Department of Pharmacy Practice and Science and an alumnus of the college. “The nasal delivery system for naloxone has shown great progress, and this funding will help support AntiOp’s efforts to create a delivery system that is easier to utilize for health care providers, friends and family members of those battling opioid addiction.”

 

As part of the grant, UK will coordinate the clinical trial for this naloxone formulation/delivery system. Faculty from the UK College of Pharmacy will analyze the naloxone nasal spray biopharmaceutics. Faculty from the UK College of Medicine’s Otolaryngology Department will study the impact on the nasal cavity.

 

“The peer-review vetting and awarding of federal support of this project provides further validation of the outstanding translational research being conducted by Dr. Wermeling and his collaborators at the University of Kentucky and by his company, AntiOp,” said Linda Dwoskin, associate dean for research for the UK College of Pharmacy. “Dr. Wermeling’s passion to bring naloxone nasal spray to patients who need it is inspiring, and we certainly applaud him for receiving this critical federal funding to support this endeavor.”

 

AntiOp is a “virtual” small pharmaceutical company with the sole purpose of developing the naloxone nasal spray with the goal of reducing national mortality from opioid overdoses, whether from licit or illicit usage. Wermeling supervises a team of scientific and regulatory experts at UK and from around the country to develop the product, manages the regulatory strategy, and is preparing for commercial manufacturing. AntiOp has an option to license the UK intellectual property on this product, and is currently seeking a partner to license and commercially market the product. 

 

In addition to this funding, AntiOp has received grant support from the Kentucky SBIR/STTR Matching Funds Program. The program is funded by the Kentucky Cabinet for Economic Development and Office of Commercialization and Innovation to support and incubate high-tech entrepreneurship in the Commonwealth of Kentucky.  

150370219.jpg
November
 
 
 
 
 
 
1
Free Saturday Swing Dance Lessons
College of Pharmacy Open House
Iron Pour
UK Women's Choir 20th Anniversary Concert
Adventure Hiking & Rappelling @ Red River Gorge
Pickin' Time Mountain Music and Harvest Day
Purposeful Retirement: Planning Your Next Stage of Life
Diwali Dhoom 2014
Sat
2
UK Percussion Ensemble
Day Hike
Curator Tour: Take My Word For It
Sun
3
Industry Career Week: Resumes and Cover Letters
Kentucky Volleyball vs. Morehead State
Mon
4
Industry Career Week: How to Impress Your Boss in 90 Days
Rock Star Professionalism Series
UK Lab Band
Tue
5
Industry Career Week: Networking and Job Search
Social Enterprise and Innovation / Certified Nonprofit Professional Program Informational Meeting
Circle of Love Name Distribution
Appalachian Forum with Dr. Fran Ansley
Dana Harper Gallery Reception
Wed
6
Career Assessment Workshop
LNFS Presents: Zona Sur
LNFS Presents: The Grand Budapest Hotel
UK Jazz Ensemble
Circle of Love Name Distribution
Abstract Workshop
Lauren Potter
Thu
7
LNFS Presents: V for Vendetta
Last Day to Withdraw or Reduce Course Load
Circle of Love Name Distribution
R.C. May Photography Lecture Series: Marvin Heiferman
Men's Soccer vs. Charlotte
Kentucky Volleyball vs. Georgia
Free Friday Evening Swing Dance
Fri
8
Kentucky Football vs. Georgia
Free Saturday Swing Dance Lessons
The Power of Poetry
The Lexington Lowdown and Free Lindy Hop Workshop
Swing Dance Featuring Live music by"The Metrognomes Orchestra"
Sat
9
UK Combos Concert
Kentucky Volleyball vs. Missouri
Sun
10
Circle of Love Name Distribution
Mon
11
UK Sax Ensembles
Job Club - Interviewing Strategies
Undergraduate Research Information Session
Jose Abisambra Presentation on Current Alzheimer's Research
Women of the World: Judy Smith
Tue
12
Internship Info Session
LNFS Presents: Reservoir Dogs
Refugee Life in America
#UKEDTALKS: International Opportunities for Education Majors
Leadership Assessment
Wed
13
Career Assessment Workshop
LNFS Presents: Iron Man 3
Chili and Pie Cook-Off Supper
#TrendingTopics: Vegetarians vs. Meat-Eaters
Campus Polar Plunge to benefit Special Olympics KY
LNFS Presents: La Demora
Thu
14
LNFS Presents: Pretty in Pink
LNFS Presents: Mean Girls
Fri
15
Free Saturday Swing Dance Lessons
Sat
16
Kentucky Volleyball vs. Florida
Greek Cinematography: Critical Approach and Discussion
"Storied Streets" Documentary Showing about Experiences of Homelessness
Sun
17
The Vexillology (the study of maps) Contest
UK Rep Bands Concert
College of Agriculture, Food & Environment 2014 Celebration of Land-Grant Research
Amanda Rogers, "Black Flags, ISIS 'Swag' & Jihadi Rap: Marketing Militancy after the Arab Spring"
Stories of Homelessness: Panel Discussion
Mon
18
The Vexillology (the study of maps) Contest
A Positive Approach to Caregiving Conference
Education Abroad Open House
CatWatch Party
Appalachian Forum and Film Screening of "Up the Ridge"
Tue
19
The Vexillology (the study of maps) Contest
LNFS Presents: The Princess and the Frog
Pinterest Party
International Games Day
Global Design with Phil Duncan
Caregiver Support Group
OXFAM Social Issues Banquet
Wed
20
The Vexillology (the study of maps) Contest
Much Ado About Nothing
LNFS Presents: I Travel Because I Have To, I Come Back Because I Love You
LNFS Presents: The Big Lebowski
International Education Week Keynote Speaker: Christie Vilsack, Senior Advisor for International Education at USAID
Tobacco-free Tailgate 5 Year Anniversary
Bollywood Night
Thu
21
The Vexillology (the study of maps) Contest
Much Ado About Nothing
LNFS Presents: Water For Elephants
4th Annual Markesbery Symposium on Aging & Dementia
Freedom from Fear: On Black Childhood and Other Dangers
Bouldering @ Stone Fort
MEAT.
Fri
22
The Vexillology (the study of maps) Contest
Much Ado About Nothing
Bouldering @ Stone Fort
Free Saturday Swing Dance Lessons
Sat
23
The Vexillology (the study of maps) Contest
Much Ado About Nothing
Bouldering @ Stone Fort
UK Symphony Band and UK Concert Band
Sun
24
The Vexillology (the study of maps) Contest
Free Thanksgiving Shuttle to Blue Grass Airport
Mon
25
Free Thanksgiving Shuttle to Blue Grass Airport
Job Club - What is your money habitude?
Multicultural Student Thanksgiving Dinner
Tue
26
Thanksgiving - Academic Holidays
Free Thanksgiving Shuttle to Blue Grass Airport
Wed
27
Thanksgiving - Academic Holidays
Thu
28
Thanksgiving - Academic Holidays
Fri
29
Thanksgiving - Academic Holidays
Free Saturday Swing Dance Lessons
Kentucky Volleyball vs. Arkansas
Sat
30
 
Sun
 
 
 
 
 
 

Thu, 11/20/2014

Fri, 11/21/2014 - Sun, 11/23/2014

Reset Page