Allison Perry

By

College: Medicine

Pediatric Cancer Treatment Has Seen Huge Advances

Published: Feb 19, 2013

 

LEXINGTON, Ky. (Feb. 19, 2013) - The following column appeared in the Lexington Herald-Leader on Sunday, Feb. 17, 2013.

 

By Dr. Lars Wagner


Although cancer is a leading cause of life-threatening disease in children, treatment has improved dramatically over the past four decades. This is because childhood tumors are often more responsive to therapy than adult cancers, and children can tolerate more intense treatment regimens. Additionally, children are often treated on large national clinical trials that pool results and allow for effective regimens to be identified more rapidly.


What causes cancer in children?


While some cancers run in families, the majority arise in previously healthy children and families. Changes in the genetic material of certain cells make them become cancerous, but the cause remains mostly unknown.


How is pediatric cancer treated?


As with adults, the main methods include surgery, chemotherapy and radiation. Some cancers can be successfully treated with surgery alone, but most require chemotherapy for the best chance of long-term cure.


Radiation is often used for treatment of brain tumors, and is combined with chemotherapy to treat tumors in other organs. Leukemia comprises up to one-third of all childhood cancers, and is generally treated solely with chemotherapy.


Bone marrow transplantation can increase the intensity of chemotherapy and is reserved for patients with very high-risk leukemia or neuroblastoma.


Because treatments are becoming more successful, and because children are at risk for long-term complications, the challenge in pediatric oncology is to use just enough treatment to be successful, while reducing risks from excessive therapy.


Pediatric cancers have a unique biology, and these young patients are best treated with specialized care from a multidisciplinary group of pediatric physicians, nurses, and staff.


How deadly is pediatric cancer?


Cure rates for acute lymphoblastic leukemia, the most common type of childhood cancer, have increased from less than 20 percent in the 1960s to the current rate of more than 80 percent.


Nevertheless, progress remains slow for certain types of cancer, particularly if the tumor has already spread at the time of diagnosis or returns after initial therapy, and much work remains to be done.


Are pediatric cancer survivors more likely to develop cancer again later in life?


Unfortunately, yes. Children who have been treated for one type of cancer are at a greater risk for developing other cancers as they grow older. They are also at a greater risk for other health issues, including heart and lung problems, altered growth and development, and learning problems.


Dr. Lars Wagner is the chief of the Division of Pediatric Hematology/ Oncology at UK HealthCare.


You Can Help


Feb. 22-23 marks the 8th DanceBlue 24-hour dance-athon to raise money to fight pediatric cancer. This student-run event has raised more than $3.5 million to support research and patients and families affected by cancer. For more information, visit DanceBlue.org  . 

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Chester Cornett: Beyond the Narrow Sky
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Swing Dance After You Graduate
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Chester Cornett: Beyond the Narrow Sky
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Chester Cornett: Beyond the Narrow Sky
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Vivian Maier: On the Street
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Other Streets: Photographs from the Collection
Job Club: Panel of Successful Job Club Members
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Chester Cornett: Beyond the Narrow Sky
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Chester Cornett: Beyond the Narrow Sky
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Chester Cornett: Beyond the Narrow Sky
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Chester Cornett: Beyond the Narrow Sky
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Other Streets: Photographs from the Collection
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Chester Cornett: Beyond the Narrow Sky
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Plant and yard Sale
PharmD Open House
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Other Streets: Photographs from the Collection
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Healthy Smoothie Demonstration
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Chester Cornett: Beyond the Narrow Sky
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Other Streets: Photographs from the Collection
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Get Moving - A Walking Group for Caregivers
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Chester Cornett: Beyond the Narrow Sky
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Other Streets: Photographs from the Collection
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UK Appreciation Day
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Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Curator Tour of VIVIAN MAIER and OTHER STREETS
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Chester Cornett: Beyond the Narrow Sky
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Chester Cornett: Beyond the Narrow Sky
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Vivian Maier: On the Street
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Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
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Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
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Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
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Vivian Maier: On the Street
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Vivian Maier: On the Street
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Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
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Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
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Chester Cornett: Beyond the Narrow Sky
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Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
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Vivian Maier: On the Street
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Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
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Vivian Maier: On the Street
Vivian Maier: On the Street
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
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Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
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Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Job Club: There is an App for That…Integrating Technology into Your Personal Finances
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Healthy Smoothie Demonstration
Healthy Smoothie Demonstration
Healthy Smoothie Demonstration
Vivian Maier: On the Street
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
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Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
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Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
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Vivian Maier: On the Street
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
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Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
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Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Thu
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Vivian Maier: On the Street
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
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Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Fri
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Vivian Maier: On the Street
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
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Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
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Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Family Say at the Art Museum
Sat
31
Vivian Maier: On the Street
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Chester Cornett: Beyond the Narrow Sky
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
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Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
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Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Vivian Maier: On the Street
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Other Streets: Photographs from the Collection
Sun
 
 
 
 
 
 

Repeats every day on May, June, July every Sunday and every Tuesday and every Wednesday and every Thursday and every Friday and every Saturday until Sun Jul 26 2015 .
Sun, 05/24/2015

Repeats every day on May, June, July every Sunday and every Tuesday and every Wednesday and every Thursday and every Friday and every Saturday until Sun Jul 26 2015 .
Tue, 05/26/2015

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