Allison Perry

By

College: Pharmacy

Shu Receives Presentation Award at National Nanotechnology Meeting

Published: Dec 6, 2012

LEXINGTON, Ky. (Dec. 6, 2012) — University of Kentucky researcher Yi Shu was awarded the Best Poster Presentation at the National Cancer Institute Alliance for Nanotechnology in Cancer's Annual Principal Investigators' Meeting last month.

 

Entitled "Fabrication of Versatile RNA Nanoparticles Targeting to Cancer without Entering Normal Organs and Tissues," Shu's study showed promise for developing ultrastable RNA nanoparticles that may help treat cancer by regulating cell function and targeting to tumors without accumulating in normal organs and tissues.

 

The study focused on using re-engineered RNA fragments as the building block to fabricate versatile nanoparticles carrying therapeutic and diagnostic modules. The RNA nanoparticles have a well-defined structure and size. They are polyvalent in nature, which allows simultaneous delivery of multiple functional molecules for synergistic treatment.

 

In addition, they are thermodynamically and chemically stable, which keeps the RNA nanoparticles intact in circulation systems at very low concentrations and confers resistance to degradation.

 

Shu is a postdoc in the laboratory of Peixuan Guo, William S. Farish Endowed Chair in Nanobiotechnology in the UK College of Pharmacy and the UK Markey Cancer Center. In collaboration with Dr. Mark Evers, director of the UK Markey Cancer Center, Guo's team focuses much of their work on the use of ribonucleic acid (RNA) nanoparticles and a viral nano-motor to fight cancer, viral infections and genetic diseases.

 

The NCI's Alliance for Nanotechnology in Cancer program was launched in 2005 on the premise that nanotechnology-based materials and devices can strongly benefit cancer research and clinical oncology. Since then, the Alliance has leveraged the talent of a multidisciplinary community developing new solutions in early detection, in vivo imaging, and multifunctional therapeutics. Several newly developed technologies are entering clinical trials with the hope of benefit to patients.

 

Significant contributors to this work include research associate professor Dan Shu and research assistant professor Farzin Haque, both part of Guo’s research team, and Dr. Piotr Rychahou, a research assistant professor on Evers' team at Markey.

 

MEDIA CONTACT: Allison Perry, (859) 323-2399 or allison.perry@uky.edu

 

yi_shu.jpgguo_group.jpg
November
 
 
 
 
 
 
1
Free Saturday Swing Dance Lessons
College of Pharmacy Open House
Iron Pour
UK Women's Choir 20th Anniversary Concert
Adventure Hiking & Rappelling @ Red River Gorge
Pickin' Time Mountain Music and Harvest Day
Purposeful Retirement: Planning Your Next Stage of Life
Diwali Dhoom 2014
Sat
2
UK Percussion Ensemble
Day Hike
Curator Tour: Take My Word For It
Sun
3
Industry Career Week: Resumes and Cover Letters
Kentucky Volleyball vs. Morehead State
Mon
4
Industry Career Week: How to Impress Your Boss in 90 Days
Rock Star Professionalism Series
UK Lab Band
Tue
5
Industry Career Week: Networking and Job Search
Social Enterprise and Innovation / Certified Nonprofit Professional Program Informational Meeting
Dana Harper Gallery Reception
Wed
6
Career Assessment Workshop
LNFS Presents: Zona Sur
LNFS Presents: The Grand Budapest Hotel
UK Jazz Ensemble
Abstract Workshop
Lauren Potter
Thu
7
LNFS Presents: V for Vendetta
Last Day to Withdraw or Reduce Course Load
R.C. May Photography Lecture Series: Marvin Heiferman
Men's Soccer vs. Charlotte
Kentucky Volleyball vs. Georgia
Free Friday Evening Swing Dance
Fri
8
Kentucky Football vs. Georgia
Free Saturday Swing Dance Lessons
The Power of Poetry
The Lexington Lowdown and Free Lindy Hop Workshop
Swing Dance Featuring Live music by"The Metrognomes Orchestra"
Sat
9
UK Combos Concert
Kentucky Volleyball vs. Missouri
Sun
10
 
Mon
11
UK Sax Ensembles
Job Club - Interviewing Strategies
Undergraduate Research Information Session
Jose Abisambra Presentation on Current Alzheimer's Research
Women of the World: Judy Smith
Tue
12
Internship Info Session
LNFS Presents: Reservoir Dogs
Refugee Life in America
Leadership Assessment
Wed
13
Career Assessment Workshop
LNFS Presents: Iron Man 3
#TrendingTopics: Vegetarians vs. Meat-Eaters
Campus Polar Plunge to benefit Special Olympics KY
LNFS Presents: La Demora
Thu
14
LNFS Presents: Pretty in Pink
LNFS Presents: Mean Girls
Fri
15
Free Saturday Swing Dance Lessons
Sat
16
Kentucky Volleyball vs. Florida
Greek Cinematography: Critical Approach and Discussion
"Storied Streets" Documentary Showing about Experiences of Homelessness
Sun
17
UK Rep Bands Concert
Stories of Homelessness: Panel Discussion
Mon
18
A Positive Approach to Caregiving Conference
CatWatch Party
Tue
19
LNFS Presents: The Princess and the Frog
Pinterest Party
Caregiver Support Group
OXFAM Social Issues Banquet
Wed
20
Much Ado About Nothing
LNFS Presents: I Travel Because I Have To, I Come Back Because I Love You
LNFS Presents: The Big Lebowski
Bollywood Night
Thu
21
Much Ado About Nothing
LNFS Presents: Water For Elephants
4th Annual Markesbery Symposium on Aging & Dementia
Freedom from Fear: On Black Childhood and Other Dangers
Bouldering @ Stone Fort
Fri
22
Much Ado About Nothing
Bouldering @ Stone Fort
Free Saturday Swing Dance Lessons
Sat
23
Much Ado About Nothing
Bouldering @ Stone Fort
UK Symphony Band and UK Concert Band
Sun
24
Free Thanksgiving Shuttle to Blue Grass Airport
Mon
25
Free Thanksgiving Shuttle to Blue Grass Airport
Job Club - What is your money habitude?
Tue
26
Thanksgiving - Academic Holidays
Free Thanksgiving Shuttle to Blue Grass Airport
Wed
27
Thanksgiving - Academic Holidays
Thu
28
Thanksgiving - Academic Holidays
Fri
29
Thanksgiving - Academic Holidays
Free Saturday Swing Dance Lessons
Kentucky Volleyball vs. Arkansas
Sat
30
 
Sun
 
 
 
 
 
 

Sat, 11/01/2014

Sun, 11/02/2014

Reset Page