Allison Perry

By

College: Pharmacy

Shu Receives Presentation Award at National Nanotechnology Meeting

Published: Dec 6, 2012

LEXINGTON, Ky. (Dec. 6, 2012) — University of Kentucky researcher Yi Shu was awarded the Best Poster Presentation at the National Cancer Institute Alliance for Nanotechnology in Cancer's Annual Principal Investigators' Meeting last month.

 

Entitled "Fabrication of Versatile RNA Nanoparticles Targeting to Cancer without Entering Normal Organs and Tissues," Shu's study showed promise for developing ultrastable RNA nanoparticles that may help treat cancer by regulating cell function and targeting to tumors without accumulating in normal organs and tissues.

 

The study focused on using re-engineered RNA fragments as the building block to fabricate versatile nanoparticles carrying therapeutic and diagnostic modules. The RNA nanoparticles have a well-defined structure and size. They are polyvalent in nature, which allows simultaneous delivery of multiple functional molecules for synergistic treatment.

 

In addition, they are thermodynamically and chemically stable, which keeps the RNA nanoparticles intact in circulation systems at very low concentrations and confers resistance to degradation.

 

Shu is a postdoc in the laboratory of Peixuan Guo, William S. Farish Endowed Chair in Nanobiotechnology in the UK College of Pharmacy and the UK Markey Cancer Center. In collaboration with Dr. Mark Evers, director of the UK Markey Cancer Center, Guo's team focuses much of their work on the use of ribonucleic acid (RNA) nanoparticles and a viral nano-motor to fight cancer, viral infections and genetic diseases.

 

The NCI's Alliance for Nanotechnology in Cancer program was launched in 2005 on the premise that nanotechnology-based materials and devices can strongly benefit cancer research and clinical oncology. Since then, the Alliance has leveraged the talent of a multidisciplinary community developing new solutions in early detection, in vivo imaging, and multifunctional therapeutics. Several newly developed technologies are entering clinical trials with the hope of benefit to patients.

 

Significant contributors to this work include research associate professor Dan Shu and research assistant professor Farzin Haque, both part of Guo’s research team, and Dr. Piotr Rychahou, a research assistant professor on Evers' team at Markey.

 

MEDIA CONTACT: Allison Perry, (859) 323-2399 or allison.perry@uky.edu

 

yi_shu.jpgguo_group.jpg
December
 
1
Resumes and Cover Letters
Circle of Love Gift Return
Mon
2
UK Guitar Studio
Circle of Love Gift Return
Tue
3
Networking and Job Search
Internship Info Session
LNFS Presents: Wayne's World
Study Sounds: Classical Concert
Wed
4
LNFS Presents: Frozen
Ballet Music of Tchaikovsky
Circle of Love Gift Pick-Up
Live Screening of Orion Spacecraft Re-entry
Massage on the Go
Thu
5
LNFS Presents: Winter's Bone
LNFS Presents: Gremlins
Open Studio
Circle of Love Gift Pick-Up
Fri
6
Snow Skiing @ Perfect North Slopes
Sat
7
Free Holiday Shopping Shuttle to Fayette Mall
Sun
8
Undergraduate Research Information Session "How to Find a Faculty Mentor"
Mon
9
Job Club - Identifying Your Skills
Paws for Stress Relief
Tue
10
 
Wed
11
 
Thu
12
Last Day of Classes
Fri
13
 
Sat
14
Free Holiday Shopping Shuttle to Fayette Mall
Finals Treats
Sun
15
Final Exams
Crunch Brunch
Mon
16
Final Exams
Jazzy Holiday Concert
Tue
17
Final Exams
Caregiver Support Group
Wed
18
Final Exams
Thu
19
Final Exams
End of 2014 Fall Semester
Fri
20
 
Sat
21
 
Sun
22
 
Mon
23
 
Tue
24
 
Wed
25
 
Thu
26
 
Fri
27
 
Sat
28
 
Sun
29
 
Mon
30
 
Tue
31
 
Wed
 
 
 
Jan 14
Bicycle Trivia 01/14/2015

Wed, 01/14/2015

Fri, 01/16/2015

Wed, 01/21/2015

Reset Page