Allison Perry

By

College: Pharmacy

Shu Receives Presentation Award at National Nanotechnology Meeting

Published: Dec 6, 2012

LEXINGTON, Ky. (Dec. 6, 2012) — University of Kentucky researcher Yi Shu was awarded the Best Poster Presentation at the National Cancer Institute Alliance for Nanotechnology in Cancer's Annual Principal Investigators' Meeting last month.

 

Entitled "Fabrication of Versatile RNA Nanoparticles Targeting to Cancer without Entering Normal Organs and Tissues," Shu's study showed promise for developing ultrastable RNA nanoparticles that may help treat cancer by regulating cell function and targeting to tumors without accumulating in normal organs and tissues.

 

The study focused on using re-engineered RNA fragments as the building block to fabricate versatile nanoparticles carrying therapeutic and diagnostic modules. The RNA nanoparticles have a well-defined structure and size. They are polyvalent in nature, which allows simultaneous delivery of multiple functional molecules for synergistic treatment.

 

In addition, they are thermodynamically and chemically stable, which keeps the RNA nanoparticles intact in circulation systems at very low concentrations and confers resistance to degradation.

 

Shu is a postdoc in the laboratory of Peixuan Guo, William S. Farish Endowed Chair in Nanobiotechnology in the UK College of Pharmacy and the UK Markey Cancer Center. In collaboration with Dr. Mark Evers, director of the UK Markey Cancer Center, Guo's team focuses much of their work on the use of ribonucleic acid (RNA) nanoparticles and a viral nano-motor to fight cancer, viral infections and genetic diseases.

 

The NCI's Alliance for Nanotechnology in Cancer program was launched in 2005 on the premise that nanotechnology-based materials and devices can strongly benefit cancer research and clinical oncology. Since then, the Alliance has leveraged the talent of a multidisciplinary community developing new solutions in early detection, in vivo imaging, and multifunctional therapeutics. Several newly developed technologies are entering clinical trials with the hope of benefit to patients.

 

Significant contributors to this work include research associate professor Dan Shu and research assistant professor Farzin Haque, both part of Guo’s research team, and Dr. Piotr Rychahou, a research assistant professor on Evers' team at Markey.

 

MEDIA CONTACT: Allison Perry, (859) 323-2399 or allison.perry@uky.edu

 

yi_shu.jpgguo_group.jpg
July
 
 
1
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Tue
2
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Get Moving - A Walking Group for Caregivers
Wed
3
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Thu
4
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Fri
5
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Sat
6
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Artful Sunday: Benday Dot Day
Sun
7
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Mon
8
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Tue
9
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Get Moving - A Walking Group for Caregivers
Wed
10
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Thu
11
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Fri
12
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
International Youth Water Justice Summit
Sat
13
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Sun
14
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Mon
15
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Tue
16
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Get Moving - A Walking Group for Caregivers (with Dr. Greg Jicha)
Wed
17
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Thu
18
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Fri
19
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Color Water Balloon Fight
Sat
20
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Summer Salon: Landscape as Subject with Tom Barnes, Photographer
Sun
21
EPIC Ministry Weekly Gathering
Mon
22
Landscape/Mindscape: Selections from the Wells Fargo Collection
Tue
23
Landscape/Mindscape: Selections from the Wells Fargo Collection
Get Moving - A Walking Group for Caregivers
Wed
24
Landscape/Mindscape: Selections from the Wells Fargo Collection
Thu
25
Landscape/Mindscape: Selections from the Wells Fargo Collection
Fri
26
Landscape/Mindscape: Selections from the Wells Fargo Collection
Sat
27
Landscape/Mindscape: Selections from the Wells Fargo Collection
Sun
28
 
Mon
29
Landscape/Mindscape: Selections from the Wells Fargo Collection
Tue
30
Landscape/Mindscape: Selections from the Wells Fargo Collection
Get Moving - A Walking Group for Caregivers (with Mary Crowley Schmidt)
Wed
31
Landscape/Mindscape: Selections from the Wells Fargo Collection
Thu
 
 

Repeats every day on May, June, July, August every Tuesday and every Wednesday and every Thursday and every Friday and every Saturday and on the first Sunday until Sun Aug 17 2014 .
Tue, 07/29/2014

Repeats every day on May, June, July, August every Tuesday and every Wednesday and every Thursday and every Friday and every Saturday and on the first Sunday until Sun Aug 17 2014 .
Wed, 07/30/2014

Repeats every day on May, June, July, August every Tuesday and every Wednesday and every Thursday and every Friday and every Saturday and on the first Sunday until Sun Aug 17 2014 .
Thu, 07/31/2014

Repeats every day on May, June, July, August every Tuesday and every Wednesday and every Thursday and every Friday and every Saturday and on the first Sunday until Sun Aug 17 2014 .
Fri, 08/01/2014

Reset Page