Sarah Geegan

By

College: Arts and Sciences

Chemistry Professor Awarded Grant From National Science Foundation

Published: May 25, 2012

LEXINGTON, Ky. (May 25, 2012) Chemistry Professor Yinan Wei recently received a $450,000 grant from the National Science Foundation for a study expected to generate some of the first ever data in her subject matter.

 

The proposal, titled "Protein Activity and Oligomer Stability in Cell Membrane," will focus on questions surrounding how proteins oligomerize in cell membrane, or in other words, how membrane-spanning proteins that function in units containing more than one subunit, assemble in nature.

 

"The selective permeability of cell membranes, which is essential for all life forms that we know, is conferred by membrane proteins," Wei said. "Approximately 80 percent of membrane proteins with known structures exist as oligomers when crystallized, indicating a large portion of proteins function as oligomers in cell membrane."

 

A thorough understanding of these questions will immensely impact several research areas, Wei said. These areas include the biogenesis of cell membrane; establishment of homeostasis; signal transduction and material transport across cell membranes; and regulation of protein functions in membranes.

 

"The study is expected to generate some of the first data concerning the correlation between oligomer stability of multi-domain and multi-span helical membrane proteins and their in vivo activity," Wei said.

 

With the current funding rate in her division, molecular and cellular biology, at approximately 14 percent, Wei said that she was excited to accept the grant, which will also allow her to train students ranging from high school to graduate levels.

 

Students will be trained to research questions in the area of membrane protein structure, function, folding and interaction. Wei said that the project will provide the students with hands-on experience about research in modern biochemistry, and that she hopes it will inspire them to pursue a career in science.

 

"This grant will allow us to do the exciting project, while in the meantime training students." Wei said. "I am thrilled."

 

 

 

MEDIA CONTACT: Sarah Geegan, (859) 257-5365; sarah.geegan@uky.edu

chemistry.jpg
April
 
 
 
1
LNFS Presents: Inherent Vice
Wildcat Wellness: Meditation
Successful Networking & Job Search
Tanya Habjouqa: Recent Photographs
Edward Troye: Theme & Variation
Same Difference: Michelle Grabner, Simone Leigh & Russell Maltz
Lexington Tattoo Project
Brazilian Conversation Hour
The Arboretum presents a Party for the Planet! Celebrate Kentucky's Past
Mr. PharmD Pageant 2015
Wed
2
LNFS Presents: Manakamana
LNFS Presents: Donnie Darko
National Student Exchange (NSE) Info Session
Tanya Habjouqa: Recent Photographs
Edward Troye: Theme & Variation
Same Difference: Michelle Grabner, Simone Leigh & Russell Maltz
Lexington Tattoo Project
Wildcat Wellness: Healthy Habits
SEC-ACC Virtual Career Fair
Massage on the Go #3
Thu
3
Cultural Coffee Hour
Tanya Habjouqa: Recent Photographs
Edward Troye: Theme & Variation
Same Difference: Michelle Grabner, Simone Leigh & Russell Maltz
Lexington Tattoo Project
Fri
4
Free Saturday Swing Dance Lessons
Tanya Habjouqa: Recent Photographs
Edward Troye: Theme & Variation
Same Difference: Michelle Grabner, Simone Leigh & Russell Maltz
Lexington Tattoo Project
Sat
5
Tanya Habjouqa: Recent Photographs
Edward Troye: Theme & Variation
Same Difference: Michelle Grabner, Simone Leigh & Russell Maltz
Lexington Tattoo Project
Sun
6
Wildcat Wellness: Expressions (Creative Stress Relief)
Age Friendly Community Panel
Resumes & Cover Letters that Work
Mon
7
National Student Exchange (NSE) Info Session
Wildcat Wellness: Relaxation
Tanya Habjouqa: Recent Photographs
Edward Troye: Theme & Variation
Same Difference: Michelle Grabner, Simone Leigh & Russell Maltz
Lexington Tattoo Project
Tue
8
LNFS Presents: The Godfather
Wildcat Wellness: Meditation
Internship Info Session
Tanya Habjouqa: Recent Photographs
Edward Troye: Theme & Variation
Same Difference: Michelle Grabner, Simone Leigh & Russell Maltz
Lexington Tattoo Project
Brazilian Conversation Hour
UK Remembers
SpeakBlue: Richard Sherman
Wed
9
LNFS Presents: The Shawshank Redemption
Tanya Habjouqa: Recent Photographs
Edward Troye: Theme & Variation
Same Difference: Michelle Grabner, Simone Leigh & Russell Maltz
Lexington Tattoo Project
Wildcat Wellness: Healthy Habits
From Plows to Plates: A Journey Through Kentucky Foodways
Workshop on Publishing
Teached Documentary
Thu
10
LNFS Presents: Enemy
LNFS Presents: Seven Psychopaths
Cultural Coffee Hour
Last Day to Withdraw or Reduce Course Load
Tanya Habjouqa: Recent Photographs
Edward Troye: Theme & Variation
Same Difference: Michelle Grabner, Simone Leigh & Russell Maltz
Lexington Tattoo Project
Robert C. May Photography Endowment Lecture: Julian Cox
Fri
11
Free Saturday Swing Dance Lessons
Tanya Habjouqa: Recent Photographs
Edward Troye: Theme & Variation
Same Difference: Michelle Grabner, Simone Leigh & Russell Maltz
Lexington Tattoo Project
fab-ric-ate Exhibit
Sat
12
Tanya Habjouqa: Recent Photographs
Edward Troye: Theme & Variation
Same Difference: Michelle Grabner, Simone Leigh & Russell Maltz
Lexington Tattoo Project
Kentucky's Present - Learn about the Bluegrass region of the Walk Across Kentucky and about invasive plants that threaten Kentucky landscapes
Sun
13
Wildcat Wellness: Expressions (Creative Stress Relief)
Don't Ask, Don't Tell
Get Your DIY On! Fix-It Station Demonstrations
Mon
14
Wildcat Wellness: Relaxation
Job Club - LinkedIn: Your Job Search Best Friend
Tie Dye Tuesday
#UK Kick Butts Day
Career & Major Exploration Session @ 1 p.m.
Career & Major Exploration Session @ 2 p.m.
Career & Major Exploration Session @ 3 p.m.
Take Back the Night Lexington
Tue
15
LNFS Presents: The Godfather: Part II
Wildcat Wellness: Meditation
Brazilian Conversation Hour
Career & Major Exploration Session @ 11 a.m.
Career & Major Exploration Session @ Noon
Career & Major Exploration Session @ 1 p.m.
Affrilachian Poets
Bike-In Movie: The Bicycle Thieves
Wed
16
LNFS Presents: The Perks of Being a Wallflower
Wildcat Wellness: Healthy Habits
CANCELED: Bike-In Breakfast
Human Rights in China: a panel discussion
Thu
17
LNFS Presents: North by Northwest
LNFS Presents: Raiders of the Lost Ark
Cultural Coffee Hour
Car-Free Day
Performance Conference
Audience Appeals and Performing Assistance Conference
Holi: The Indian Festival of Colors
Fri
18
Free Saturday Swing Dance Lessons
Bully Breed Awareness Walk
Spring Carnival 2015
Taste of Africa
GAYla Drag Show and Silent Auction
Sat
19
 
Sun
20
Wildcat Wellness: Expressions (Creative Stress Relief)
Floral Sculpture
Pinterest Party #3
Mon
21
Wildcat Wellness: Relaxation
Student Center "Farewell" Informational Fair
Tour de Downtown Art
Tue
22
LNFS Presents: Birdman
Wildcat Wellness: Meditation
National Student Exchange (NSE) Info Session
Brazilian Conversation Hour
Healthy Smoothie Demonstration
Ping Pong Ball Drop
Shake the Stress Fest
Wed
23
LNFS Presents: Dr. Strangelove or: How I Learned to Stop Worrying and Love the Bomb
LNFS Presents: The Avengers
Wildcat Wellness: Healthy Habits
Wildcat Wrap-Up
UK Elder Care Lunch & Learn
Kentucky's Future - Plant a Tree in the Pennyrile region of the Walk Across Kentucky
Thu
24
LNFS Presents: Batman
LNFS Presents: O Brother, Where Art Thou?
Cultural Coffee Hour
Art in Bloom Weekend
Fri
25
Free Saturday Swing Dance Lessons
Network Publishing: Digital Writing in the Humanities
The Party for the Planet final event in April is Arbor Day at The Arboretum!
Art in Bloom Weekend
Art in Bloom Cocktail Party
Sat
26
Art in Bloom Weekend
Sun
27
Resumes & Cover Letters that Work
Wildcat Wellness: Expressions (Creative Stress Relief)
Fuel for Finals
UK Ag Equine Programs Distinguished Lecture Series
Mon
28
Wildcat Wellness: Relaxation
Job Club: How to Write the Perfect Resume and Cover Letter
How to Impress Your Boss: Employer Panel
Tue
29
Wildcat Wellness: Meditation
Internship Info Session
Brazilian Conversation Hour
Appalachian Research Day
Wed
30
Wildcat Wellness: Healthy Habits
Thu
 
 
Apr 21
Wildcat Wellness: Relaxation 04/21/2015

Tue, 04/21/2015

Repeats every 0 months on the fourth Wednesday until Tue Jun 30 2015 .
Wed, 04/22/2015

Wed, 04/22/2015

Repeats every week until Thu Apr 30 2015 except Wed Mar 18 2015.
Wed, 04/22/2015

Repeats every week until Wed May 06 2015 except Wed Mar 18 2015.
Wed, 04/22/2015

Reset Page