Allison Elliott-Shannon

By

College: Medicine

ScanScope Peers Into Brains

Published: May 27, 2011

LEXINGTON, KY. (May 27, 2011) — A new, exciting piece of equipment will soon be up and running in the University of Kentucky Sanders-Brown Center on Aging. The Aperio ScanScope instrument, purchased with a $283,000 grant from the National Institutes of Health, will enable Sanders-Brown researchers to study brain tissues in a new way, and to create a "digital brain bank" of data on donated brain tissue.

 

"The ScanScope represents cutting-edge digital microscopy technology that enables automated and high resolution quantitative neuropathology.  This slide scanning system will enhance our Center’s ability to detect early changes in the brain, and will greatly benefit the research programs of a large number of investigators," said Linda Van Eldik, SBCoA director.

 

The Sanders-Brown Center on Aging has been collecting brain tissue from research volunteers for more than 25 years, and has one of the world’s most complete tissue banks - from both healthy donors as well as those with Alzheimer's disease and other cognitive impairments.

 

The ScanScope will allow for digital microscopy-based reading of brain tissue changes that occur in the aged brain. Digital microscopy enables completely different new possibilities when compared with microscope readings taken with the human eye alone. Thus, the ScanScope will allow researchers to pick up extremely minute characteristics of brain tissue. The machine will give faster and more accurate readings of brain tissue, giving researchers precise knowledge of changes seen in the brain during both healthy aging and cognitive impairment.

 

"It will help us decide what changes are most sensitive and specific for different disease subtypes," said Peter Nelson, a neuropathologist at Sanders-Brown who wrote the NIH grant proposal. "This is great because one of the big findings from our center is that not all people with cognitive impairment have Alzheimer's disease.  We can ask new questions, like, ‘What is the effect of diabetes on the brain?’, and ‘Is heart disease linked to problems in the brain?’  The ScanScope has the potential to allow us to move the field forward by finding whole new brain diseases that couldn't be visualized by the naked human eye alone."

aperion_scanscope.jpg
July
 
 
1
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Tue
2
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Get Moving - A Walking Group for Caregivers
Wed
3
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Thu
4
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Fri
5
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Sat
6
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Artful Sunday: Benday Dot Day
Sun
7
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Mon
8
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Tue
9
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Get Moving - A Walking Group for Caregivers
Wed
10
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Thu
11
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Fri
12
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
International Youth Water Justice Summit
Sat
13
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Sun
14
EPIC Ministry Weekly Gathering
EPIC Ministry Weekly Gathering
Mon
15
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Tue
16
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Get Moving - A Walking Group for Caregivers (with Dr. Greg Jicha)
Wed
17
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Thu
18
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Fri
19
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Color Water Balloon Fight
Sat
20
EPIC Ministry Weekly Gathering
Landscape/Mindscape: Selections from the Wells Fargo Collection
Summer Salon: Landscape as Subject with Tom Barnes, Photographer
Sun
21
EPIC Ministry Weekly Gathering
Mon
22
Landscape/Mindscape: Selections from the Wells Fargo Collection
Tue
23
Landscape/Mindscape: Selections from the Wells Fargo Collection
Get Moving - A Walking Group for Caregivers
Wed
24
Landscape/Mindscape: Selections from the Wells Fargo Collection
Thu
25
Landscape/Mindscape: Selections from the Wells Fargo Collection
Fri
26
Landscape/Mindscape: Selections from the Wells Fargo Collection
Sat
27
Landscape/Mindscape: Selections from the Wells Fargo Collection
Sun
28
 
Mon
29
Landscape/Mindscape: Selections from the Wells Fargo Collection
Tue
30
Landscape/Mindscape: Selections from the Wells Fargo Collection
Get Moving - A Walking Group for Caregivers (with Mary Crowley Schmidt)
Wed
31
Landscape/Mindscape: Selections from the Wells Fargo Collection
Thu
 
 

Repeats every day on May, June, July, August every Tuesday and every Wednesday and every Thursday and every Friday and every Saturday and on the first Sunday until Sun Aug 17 2014 .
Wed, 07/30/2014

Repeats every day on May, June, July, August every Tuesday and every Wednesday and every Thursday and every Friday and every Saturday and on the first Sunday until Sun Aug 17 2014 .
Thu, 07/31/2014

Fri, 08/01/2014 - Wed, 09/03/2014

Repeats every day on May, June, July, August every Tuesday and every Wednesday and every Thursday and every Friday and every Saturday and on the first Sunday until Sun Aug 17 2014 .
Fri, 08/01/2014

Reset Page