Allison Elliott-Shannon

By

College: Medicine

ScanScope Peers Into Brains

Published: May 27, 2011

LEXINGTON, KY. (May 27, 2011) — A new, exciting piece of equipment will soon be up and running in the University of Kentucky Sanders-Brown Center on Aging. The Aperio ScanScope instrument, purchased with a $283,000 grant from the National Institutes of Health, will enable Sanders-Brown researchers to study brain tissues in a new way, and to create a "digital brain bank" of data on donated brain tissue.

 

"The ScanScope represents cutting-edge digital microscopy technology that enables automated and high resolution quantitative neuropathology.  This slide scanning system will enhance our Center’s ability to detect early changes in the brain, and will greatly benefit the research programs of a large number of investigators," said Linda Van Eldik, SBCoA director.

 

The Sanders-Brown Center on Aging has been collecting brain tissue from research volunteers for more than 25 years, and has one of the world’s most complete tissue banks - from both healthy donors as well as those with Alzheimer's disease and other cognitive impairments.

 

The ScanScope will allow for digital microscopy-based reading of brain tissue changes that occur in the aged brain. Digital microscopy enables completely different new possibilities when compared with microscope readings taken with the human eye alone. Thus, the ScanScope will allow researchers to pick up extremely minute characteristics of brain tissue. The machine will give faster and more accurate readings of brain tissue, giving researchers precise knowledge of changes seen in the brain during both healthy aging and cognitive impairment.

 

"It will help us decide what changes are most sensitive and specific for different disease subtypes," said Peter Nelson, a neuropathologist at Sanders-Brown who wrote the NIH grant proposal. "This is great because one of the big findings from our center is that not all people with cognitive impairment have Alzheimer's disease.  We can ask new questions, like, ‘What is the effect of diabetes on the brain?’, and ‘Is heart disease linked to problems in the brain?’  The ScanScope has the potential to allow us to move the field forward by finding whole new brain diseases that couldn't be visualized by the naked human eye alone."

aperion_scanscope.jpg
February
 
1
Graduate Student Congress Meeting (February)
Mon
2
Bill Adams: Blue Madness
Bill Adams: Blue Madness
Bill Adams: Blue Madness
Bill Adams: Blue Madness
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Open House: Selections from the John and Sue Wieland Collection
Open House: Selections from the John and Sue Wieland Collection
Open House: Selections from the John and Sue Wieland Collection
Open House: Selections from the John and Sue Wieland Collection
Open House: Selections from the John and Sue Wieland Collection
Open House: Selections from the John and Sue Wieland Collection
Open House: Selections from the John and Sue Wieland Collection
Tue
3
K Crew Recruitment
Last Day to Drop a Course Without Appearing on Transcript
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Wed
4
K Crew Recruitment
Bill Adams: Blue Madness
Undergraduate Research Information Session
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Thu
5
K Crew Recruitment
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Explore Blue
Off-Campus Student Services' Wildcat Apartment Hop #1
Panel Discussion: Historic Homes
Fri
6
K Crew Recruitment
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Sat
7
K Crew Recruitment
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Sun
8
K Crew Recruitment
Sex and Chocolate
Law School Prep Workshop
Mon
9
K Crew Recruitment
Healthy Relationships Workshop
How to Package Communication and Technical Skills on your Resume
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
2016 Distinguished Industry Lecture Series
Tue
10
K Crew Recruitment
Last Day to Receive 50% Refund
Pinterest Party #1
Off-Campus Student Association Information Session
Get Yourself Tested!
Showcase your Talents: Building a Strong Portfolio
An Evening with Tatyana Ali and Amir Windom: Progression Towards Success
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
How to Survive a Plague
Wed
11
K Crew Recruitment
Coffee & Canvases
Off-Campus Student Association Information Session
Study Abroad in Berlin!
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Thu
12
K Crew Recruitment
Explore Blue
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Fri
13
K Crew Recruitment
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Workshop: The Artist Statement
Sat
14
K Crew Recruitment
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Sun
15
K Crew Recruitment
See ICT
Patterson School Guest Speaker Series
Mon
16
K Crew Recruitment
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
See ICT
UK Women's Forum February Board Meeting
Tue
17
K Crew Recruitment
Food For Thought
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Wed
18
Undergraduate Research Information Session
Soup & Substance: Real Talk, Real Issues, & Real People Series
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Thu
19
PharmD Interviews
Explore Blue
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Off-Campus Student Services' Wildcat Apartment Hop #2
SAB Underground Formal
Fri
20
PharmD Interviews
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Sat
21
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Sun
22
Undergraduate Research Information Session
Mon
23
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Tue
24
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
UK Elder Care Lunch & Learn - Don't Blame It On Aging
Ravi Zacharias at Memorial Coliseum
Wed
25
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Thu
26
Explore Blue
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Dimensions of Political Ecology Conference
Eday Talk by Georgetown Toyota President Wil James
Do What You Are: Connecting Personalities w/ Profession
Off- Campus Student Services' Wildcat Apartment Hop #3
Concert in the Museum: Central Music Academy
Fri
27
Dimensions of Political Ecology Conference
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
UK E-Day
Sat
28
Bill Adams: Blue Madness
Bill Adams: Blue Madness
Bill Adams: Blue Madness
DanceBlue Rave Hour
Bill Adams: Blue Madness
Open House: Selections from the John and Sue Wieland Collection
Open House: Selections from the John and Sue Wieland Collection
Sun
29
Monday through Friday - Midterm Grading window is open. The mid-term grading window will close at midnight on March 11.
Monday through Wednesday - Students are prohibited from changing academic major
Bodies Of Evidence: Provocations: A Transnational Feminist History Project
Mon
 
 
 
 
 
Feb 06
Bill Adams: Blue Madness 02/06/2016

Repeats every day on January, February, March, April every Sunday and every Tuesday and every Wednesday and every Thursday and every Friday and every Saturday until Mon Apr 04 2016 .
Sun, 02/07/2016

Repeats every day on January, February, March, April every Sunday and every Tuesday and every Wednesday and every Thursday and every Friday and every Saturday until Sun Apr 03 2016 .
Sun, 02/07/2016

Mon, 02/08/2016

Repeats every day on January, February, March, April every Sunday and every Tuesday and every Wednesday and every Thursday and every Friday and every Saturday until Sun Apr 03 2016 .
Tue, 02/09/2016

Reset Page