What is hantavirus? Symptoms, spread and risk explained

A responder in a protective hooded suit wears a full-face respirator while another responder adjusts the mask straps during an emergency preparedness drill.
UK HealthCare Infection Prevention and Control led a drill for general infectious disease preparedness and readiness at Chandler Hospital. Hilary Brown | UK Photo

LEXINGTON, Ky. (May 11, 2026) — Hantavirus is a family of rare but serious viruses that can cause illnesses such as hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS).  

Currently, the World Health Organization (WHO) is monitoring a cluster of cruise ship passengers aboard the MV Hondius affected by Hantavirus — specifically a rare strain known as the Andes virus. 

As of May 7, WHO identified eight confirmed hantavirus cases, including three deaths. 

Experts from WHO, the Centers for Disease Control and Prevention (CDC) and the University of Kentucky have categorized this as a low risk to the public, but there are still ways you can stay safe. 

What is hantavirus? 

These viruses are typically spread through exposure to rodents — particularly deer mice and white footed mice in Kentucky — most commonly through rodent droppings, urine or saliva while cleaning enclosed or dusty spaces. 

Symptoms usually begin one to eight weeks after contact with an infected rodent or exposure to contaminated materials. Person-to-person transmission is uncommon. The Andes virus, found primarily in South America, has been reported to spread between people who have close contact with someone who is ill. 

In the U.S. and the Americas, it often causes severe, sometimes fatal pneumonia. In Europe and Asia, the virus is often associated with more kidney-related symptoms. As of the end of 2023, 890 hantavirus disease cases had been reported in the United States since national surveillance began in 1993.   

Early symptoms of hantavirus resemble a cold or flu, and some patients may improve at first, making this virus difficult to diagnose. 

Symptoms of HPS include: 

  • Fatigue  
  • Fever  
  • Muscle and joint aches 
  • Headaches 
  • Dizziness 
  • Chills

Symptoms of HFRS include: 

  • Intense headaches 
  • Back and abdominal pain 
  • Fever  
  • Nausea 
  • Blurred vision 

When to seek treatment 

Currently, there is no treatment for hantavirus or the Andes virus-specific strain. If you think you may have been exposed to the Andes virus and are experiencing symptoms, you should contact a healthcare provider immediately. 

How to reduce your risk 

Learning how to properly treat any area rodents that may have been present is an important step in preventing any type of infection. Following the CDC’s guidance for sealing gaps or holes, cleaning your space and using personal protective equipment can help you reduce your exposure and stay safe. 

The CDC’s steps for protecting yourself and your family from HPS are as follows.

Seal up:

  • When sealing gaps and holes inside your home look inside, underneath and behind kitchen cabinets, the corners of closets, around fireplaces and other compact areas; mice can fit through a hole the width of a pencil.  
  • It’s also critical to properly seal your pantry staples and practice proper food safety and cleanliness. Food should be stored in thick plastic, metal or glass containers with tight lids. 

Trap up: 

  • Snap traps and poison bait are common ways to control mice and rats in the home but should always be in places out of reach of children and pets. 
  • Poison bait is typically used for more severe infestations. Be sure to choose a product designed for the specific rodent problem you’re dealing with.  
  • Glue traps and live traps are not recommended because they can stress rodents, causing them to urinate more and increasing the risk of exposure for humans. 

Clean up:

  • Carefully clean rodent urine droppings and nests using disinfectant or a fresh bleach solution while wearing gloves and face protection. 
  • Never sweep or vacuum rodent waste, as this can spread any potential virus into the air; instead soak the contaminated area, wipe with paper towels and dispose of the waste. 
  • Always wash gloved hands before removing gloves and wash your hands after to reduce your exposure. 

As the state’s flagship, land-grant institution, the University of Kentucky exists to advance the Commonwealth. We do that by preparing the next generation of leaders — placing students at the heart of everything we do — and transforming the lives of Kentuckians through education, research and creative work, service and healthcare. We pride ourselves on being a catalyst for breakthroughs and a force for healing, a place where ingenuity unfolds. It's all made possible by our people — visionaries, disruptors and pioneers — who make up 200 academic programs, a $1.02 billion research and development enterprise and a world-class medical center, all on one campus.